Gene interactions and pathways from curated databases and text-mining

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ARG1 — CDKN1A

Text-mined interactions from Literome

Guo et al., J Biol Chem 2011 : A citrulline mimicking Arg-NLS-Gln ING4 mutant, which has all Arg residues in the NLS mutated to Gln, loses its affinity for p53, can no longer promote p53 acetylation, and results in repression of downstream p21 expression
Crook et al., Oncogene 1998 : Arg283His transactivates the p21Waf1 , Mdm2, bax, cyclin G and IGF-BP3 promoters in transient transfection assays equally as well as, if not better than WT p53