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MUC17 — MUC2
Text-mined interactions from Literome
Kim et al., J Korean Med Sci 2002
(MAP Kinase Signaling System) :
These results suggest that the IL-1beta mediated MUC2 gene expression and
mucin secretion in NCI-H292 cells are regulated through activation of the PKC-MEK/ERK pathway, and that PI3K is also
involved in the IL-1beta mediated
MUC2 gene expression and mucin secretion
Zhao et al., Int J Gynecol Pathol 2003
(Adenocarcinoma, Mucinous...) :
The normal endocervical epithelium was characterized by predominant sulfomucin and MUC1 expression in all sites and MUC5AC expression in the surface epithelium, while
MUC2 was not detected at all and pyloric gland type
mucin ( using antibody HIK1083 ) was
detected in less than 1 % of cases
Gaudier et al., Am J Physiol Gastrointest Liver Physiol 2004
:
In glucose deprived medium, i.e., when butyrate was the only energy source available,
MUC3 and MUC5B increase persisted, whereas MUC5AC expression was significantly enhanced ( 3.7-fold basal level ) and
MUC2 expression was strikingly
increased ( 23-fold basal level )
Alameda et al., Int J Gynecol Pathol 2007
(Hyperplasia...) :
These findings suggest that during endometrial neoplasic transformation, increased levels of MUC4,
MUC5AC , and MUC6 are
detected , whereas
MUC2 is only significantly detected in the secretory endometrium