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RGCC — SMAD2

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: RGCC — SMAD2 (physical association, affinity chromatography technology) Li et al., J Biol Chem 2011*

Text-mined interactions from Literome

Guo et al., Am J Physiol Cell Physiol 2011 : Coexpression of RGC-32 and Smad3, but not Smad2 , induces a higher mesenchymal marker a-smooth muscle actin ( a-SMA ) protein expression as compared with RGC-32 or Smad3 alone, while knockdown of Smad3 using short hairpin interfering RNA blocks RGC-32 induced a-SMA expression
Huang et al., Am J Physiol Cell Physiol 2011 : Functionally, Smad2 , but not Smad3, activated RGC-32 promoter ... These results demonstrate that Smad2 regulation of RGC-32 transcription is essential for SMC differentiation from neural crest cells