Linnemann et al., Virology 2002
:
Finally, inhibition of PI3K blocked the activation of PAK and decreased the production of viral particles to levels observed with the Nef deleted provirus
Chan et al., J Biol Chem 2008
(MAP Kinase Signaling System) :
PAK is regulated by PI3K , PIX, CDC42, and PP2Calpha and mediates focal adhesion turnover in the hyperosmotic stress induced p38 pathway