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PIK3CA — PKD1

Text-mined interactions from Literome

Vigorito et al., Cell Signal 2006 : Synergistic activation of PKD by the B cell antigen receptor and CD19 requires PI3K , Vav1 and PLCgamma ... We found that PKD activation upon BCR engagement or coligation of the BCR with CD19 is entirely dependent on PI3K and PLCgamma but differ in the requirement for Vav proteins ... These findings show that Vav proteins and PI3K regulation of PLCgamma contributes to the activation of PKD in response to BCR and or CD19 cross linking
Van Lint et al., J Biol Chem 1998 : Although the presence of a pleckstrin homology domain makes PKD a potential PI3K target, PKD was not stimulated by selective PI3K activation, and wortmannin, an inhibitor of PI3K, did not inhibit PDGF signaling to PKD