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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

◀ Back to CCNE2

CCNE2 — E2F2

Pathways - manually collected, often from reviews:

  • KEGG Cell cycle: Complex of E2F1-E2F2-E2F3-TFDP1-TFDP2 → CCNE1/CCNE2 (gene expression, expression)
  • WikiPathways Retinoblastoma (RB) in Cancer: Complex of TFDP1-E2F2 → CCNE2/CDC25A/CCNE1/CCND3/CDK1/CCDC6/CCNB1 (mim-transcription-translation)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

  • STRING interaction: CCNE2 — E2F2 (interaction, mapped from kegg_pathways)
  • STRING interaction: E2F2 — CCNE2 (interaction, mapped from kegg_pathways)

Text-mined interactions from Literome

Duronio et al., Genes Dev 1995 : Instead, cyclin E expression activates E2F in the CNS
Chiarugi et al., Cell Mol Biol Res 1994 : Notably, both of the two giant regulators of checkpoint 1 ( i.e., p105RB [ retinoblastoma oncosuppressor encoded protein ] and p53 dependent WAF1/CIP1 ) are influenced by or influence G1 cyclins : cyclin E/cdk2 kinase complexes hyperphosphorylate p105RB, induce E2F release, and free G1 exit