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CRH — MAPK7

Text-mined interactions from Literome

Grammatopoulos et al., Mol Endocrinol 2000 (MAP Kinase Signaling System) : We therefore hypothesized that activation of MAPK might mediate CRH and or/urocortin actions in the myometrium
Kovalovsky et al., Mol Endocrinol 2002 (MAP Kinase Signaling System) : The MAPK kinase inhibitors did not affect Nur77 and Nurr1 mRNA induction but blocked CRH or cAMP stimulated Nur transcriptional activity ... In conclusion, in AtT-20 corticotrophs the CRH/cAMP signaling that leads to Nur77/Nurr1 mRNA induction and transcriptional activation, and thus POMC expression, is dependent on protein kinase A and involves calcium/calmodulin kinase II ( Nur induction/activation ) and MAPK calcium dependent and -independent ( Nur phosphorylation-activation ) pathways
Park et al., J Invest Dermatol 2005 (MAP Kinase Signaling System) : In addition, CRH treatment induced rapid phosphorylation of p38 MAPK ... SB203580 were able to inhibit CRH induced p38 MAPK phosphorylation
Refojo et al., Proc Natl Acad Sci U S A 2005 : Corticotropin releasing hormone activates ERK1/2 MAPK in specific brain areas
Cheng et al., Life Sci 2005 : In this study, we showed that the MAPK inhibitor, PD098059, causes a dose dependent inhibition of placental CRH gene expression
Basta-Kaim et al., Neuropharmacology 2005 (Neuroblastoma) : It was found that wortmannin ( 0.1muM ), an inhibitor of phosphatidylinositol 3-kinase (PI3-K) and forskolin ( 10, 25muM ), an activator of adenylate cyclase enhanced the basal activity of CRH gene promoter, whereas inhibitors of protein kinase A, calcium/calmodulin kinase ( CaMK ) and mitogen activated protein kinase ( MAPK ) had opposite effects
Cao et al., Mol Pharmacol 2006 : CRH also induced rapid phosphorylation of p38 MAPK , which was mimicked by 8-bromo-cAMP and was inhibited by H89 or SB203580
Swinny et al., Eur J Neurosci 2006 : The structural effects of CRF required protein kinase A and mitogen activated protein kinase , as well as Rac1, a member of the Rho family of GTPases that regulates the actin and microtubule cytoskeleton
Wang et al., Placenta 2007 : Stimulation of the cells with CRH caused a rapid and transient phosphorylation of p38/MAPK while CRH had no effect on ERK1/2 activation ... The effect of CRH on p38/MAPK activation was suppressed by astressin and by the p38/MAPK inhibitor SB203580
Zhang et al., Br J Pharmacol 2009 : These findings suggest that Ucn1 exerts pro-inflammatory effects by augmenting LPS induced expression of COX-2 and ICAM-1 in RAECs via CRF ( 2 ) receptors and the activation of p38MAPK and NF-kappaB
Zhou et al., Regul Pept 2010 : In addition, CRH treatment induced rapid phosphorylation of p38 MAPK and JNK1/2, and antalarmin, SB203580 and SP600125 inhibited CRH induced phosphorylation of p38 MAPK and JNK1/2