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DOK4 — SRC
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Van Slyke et al., Mol Cell Biol 2005
(Breast Neoplasms) :
Furthermore, we demonstrate that
Dok-R can abrogate c-Src 's ability to protect the breast cancer cell line SKBR3 from anoikis and that an association with
c-Src and Csk is
required for this activity
Itoh et al., J Biol Chem 2005
(Inflammation) :
Most interestingly, overexpression of
Dok-4-WT , but not Dok-4- ( deltaN1-99 ),
increased mitochondrial
c-Src expression, whereas knock-down of endogenous Dok-4 with a small interfering RNA vector greatly inhibited mitochondrial localization of c-Src, suggesting a unique function for Dok-4 as an anchoring protein for c-Src in mitochondria
Peng et al., Science signaling 2013
:
In response to LPS,
DOK3 was phosphorylated in a DAP12- and
Src dependent manner, which led to translocation of phosphorylated DOK3 to the plasma membrane