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Bełtowski et al., Peptides 2006
:
Leptin and H ( 2 ) O ( 2 ) increased Src phosphorylation at Tyr ( 418 )
Jamroz-Wiśniewska et al., Biochem Pharmacol 2008
(Hypertension) :
Leptin , administered in increasing doses ( 0.1-0.5 mg/kg/day ) for 10 days, increased phosphorylation levels of non-receptor tyrosine kinase, c-Src , EGF receptor and extracellular signal regulated kinases ( ERK ) in aorta and kidney, which was accompanied by the increase in plasma concentration and urinary excretion of isoprostanes and H2O2