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NOX5 — SRC

Text-mined interactions from Literome

Touyz et al., Arterioscler Thromb Vasc Biol 2003 : The aim of this study was to determine molecular mechanisms whereby c-Src regulates angiotensin II (Ang II) mediated NAD ( P ) H oxidase derived *O2- in human vascular smooth muscle cells ( VSMCs ) ... Confirmation of c-Src dependent regulation of NAD ( P ) H oxidase was tested in VSMCs from c-Src-/- mice ... c-Src regulates NAD ( P ) H oxidase derived *O2- generation acutely by stimulating p47phox phosphorylation and translocation and chronically by increasing protein content of gp91phox, p22phox, and p47phox in Ang II-stimulated cells
Callera et al., Hypertension 2005 : We tested the hypothesis that aldosterone induces activation of vascular mitogen activated protein ( MAP ) kinases and NADPH oxidase via c-Src dependent mechanisms in vascular smooth muscle cells ( VSMCs )
Abid et al., J Biol Chem 2007 : The permissive role of NADPH oxidase on phosphoinositide 3-kinase-Akt-forkhead signaling is mediated at post-VEGF receptor levels and involves the nonreceptor tyrosine kinase Src
Sampaio et al., Hypertension 2007 : Ang II-induced phosphorylation of c-Src , extracellular signal regulated kinase ( ERK ) 1/2, and SHP-2 and activation of NAD ( P ) H oxidase were assessed in the absence and presence of Ang- ( 1-7 ) ( 10 ( -6 ) mol/L, 15 minutes ) by immunoblotting and lucigenin enhanced chemiluminescence, respectively
Li et al., Biochem J 2008 : Endosomal NADPH oxidase regulates c-Src activation following hypoxia/reoxygenation injury
Montezano et al., Arterioscler Thromb Vasc Biol 2008 : Aldo and Ang II costimulation induced c-Src dependent activation of NAD ( P ) H oxidase and c-Src independent activation of ERK1/2 ( P < 0.05 ), without effect on ERK5, p38MAPK, or JNK
Gupte et al., Am J Physiol Heart Circ Physiol 2009 : Peroxide generation by p47phox-Src activation of Nox2 has a key role in protein kinase C-induced arterial smooth muscle contraction ... Thus a p47(phox) and Src kinase activation of peroxide production by Nox2 appears to be an important contributor to vascular contractile mechanisms mediated through activation of PKC
Ishizawa et al., Nephrol Dial Transplant 2010 : The NADPH oxidase inhibitors inhibited not only PDGF induced BMK1 and Src activation but also RMC migration
Lee et al., Carcinogenesis 2011 (Anoxia) : Using biochemical and genetic inhibition, we demonstrated that Src requires reduced nicotinamide adenine dinucleotide phosphate ( NADPH ) oxidase/Rac complex for stabilization of HIF-1a
Paravicini et al., Journal of the American Society of Hypertension : JASH 2012 (Disease Models, Animal...) : Acute stretch stimulated p38MAPK activation in WKY and SHR, independently of c-Src and reactive oxygen species ( ROS ), since PP2 ( c-Src inhibitor ) and apocynin ( NADPH oxidase inhibitor ), failed to alter stretch mediated p38MAPK
Tseng et al., Arch Toxicol 2012 : NADPH oxidase produced superoxide mediates EGFR transactivation by c-Src in arsenic trioxide stimulated human keratinocytes
Shi et al., Proc Natl Acad Sci U S A 1996 : PR-39, a proline-rich antibacterial peptide that inhibits phagocyte NADPH oxidase activity by binding to Src homology 3 domains of p47 phox