Gene interactions and pathways from curated databases and text-mining

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POLR2E — RAD50

Text-mined interactions from Literome

Lejeune et al., DNA repair 2009 : Elc1 has also been suggested to be present in another ubiquitin ligase complex that lacks Rad7 and Rad16 and is involved in UV-induced ubiquitylation and subsequent degradation of RNA polymerase II
Bah et al., Nucleic Acids Res 2012 : RNA polymerase II (RNAPII) associates with pombe chromosome ends in vivo and the telomeric factor Rap1 negatively regulates this association, as well as the cellular accumulation of RNA emanating from chromosome ends
Sen et al., J Biol Chem 2013 : In contrast, the loss of Rad6p significantly impairs the association of RNA polymerase II with GAL1
Ghosh-Roy et al., PloS one 2013 : Rad26 , the Transcription Coupled Repair Factor in Yeast, Is Required for Removal of Stalled RNA Polymerase-II following UV Irradiation
Guzder et al., Nature 1994 : Extract from the conditional lethal mutant rad25-ts24 exhibits a thermolabile transcriptional defect which can be corrected by the addition of RAD25 protein, indicating a direct and essential role of RAD25 in RNA polymerase II transcription