Gene interactions and pathways from curated databases and text-mining

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HDAC2 — HIF1A

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Kato et al., J Biol Chem 2004 (Anoxia) : In the nucleus, HDAC7 increased transcriptional activity of HIF-1alpha through the formation of a complex with HIF-1alpha , HDAC7, and p300
Qian et al., Cancer Res 2006 (Carcinoma, Renal Cell...) : In the current study, we investigated the molecular link between HIF-1 alpha inhibition and HDAC inhibition
Kim et al., Oncol Rep 2007 (Anoxia...) : Here, we found that a histone deacetylase inhibitor, sodium butyrate, inhibits the hypoxia induced induction and activity of HIF-1alpha in HT1080 human fibrosarcoma cells