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CNTF — MAPK13
Text-mined interactions from Literome
van Puijenbroek et al., Exp Cell Res 1999
(Carcinoma, Embryonal) :
Using a dominant negative p21ras construct and a specific inhibitor of mitogen activated protein kinase kinase ( MEK ; PD098059 ) we demonstrated that CNTF induced Stat3 transactivation was independent of the p21ras-mitogen activated protein kinase ( MAPK ) pathway, while
CNTF induced
MAPK activation was p21ras- and MEK dependent
Peterson et al., J Neurosci 2000
:
To understand its mechanism of action in vivo, the adult rat retina was used as a model to investigate
CNTF mediated activation of Janus kinase/signal transducer and activator of transcription ( Jak-STAT ) and
ras-mitogen activated protein kinase ( ras-MAPK )
Zvonic et al., J Biol Chem 2003
:
In order to investigate the effects of CNTF on fat cells, we examined the expression of CNTF receptor complex proteins ( LIFR, gp130, and CNTFRalpha ) during adipocyte differentiation and the
effects of
CNTF on STAT, Akt, and
MAPK activation
Chen et al., Mol Biol Cell 2005
:
Furthermore,
CNTF could
activate the p44/p42
MAPK and down-regulate the expression of myogenic regulatory factors ( MRFs )
Crowe et al., Endocrinology 2008
(Obesity...) :
Studies in cultured adipocytes revealed that
CNTF activates p38
MAPK and AMP activated protein kinase
Hu et al., Hepatology 2008
(Carcinoma, Hepatocellular...) :
Furthermore,
CNTF induced mitogen activated protein kinase (
MAPK )
activation suppresses AMPK activity in the early phase of CNTF stimulation
Bonni et al., Science 1997
:
Although
CNTF stimulated both the Janus kinase-signal transducer and activator of transcription ( JAK-STAT ) and
Ras-mitogen activated protein kinase signaling pathways in cortical precursor cells, the JAK-STAT signaling pathway selectively enhanced differentiation of these precursors along a glial lineage