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LCN2 — RELA
Text-mined interactions from Literome
Cowland et al., J Immunol 2003
:
TNF-alpha activation of
NF-kappaB , in contrast, did not
increase NGAL synthesis, even though induced binding of NF-kappaB to the
NGAL promoter was observed in vitro
Sousa et al., FASEB J 2005
(Amyloid Neuropathies, Familial) :
Biglycan,
NGAL , and MMP-9 are transcriptionally
up-regulated by
NF-kappaB , a transcription factor that is activated in FAP nerves and SG
Bu et al., Am J Pathol 2006
(Carotid Artery Injuries) :
The present study reveals a previously unrecognized vascular response to an-gioplastic injury, characterized by
NF-kappaB dependent expression of
NGAL in vascular SMCs. Further-more, SMC produced NGAL interacts with MMP-9, a mechanism by which NGAL may modulate MMP-9 proteolytic activity in the vascular repair process
Matsuo et al., Biochem J 2007
:
The
activation of the
NGAL promoter by transfection of IkappaB-zeta and
NF-kappaB was suppressed in C/EBPbeta depleted cells
Bolignano et al., Cancer Lett 2010
(Neoplasm Invasiveness...) :
Moreover, in thyroid carcinomas,
NGAL is strongly
induced by
NF-kB , an important factor involved both in tumor growth and in the link between chronic inflammation and neoplastic development