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CDH23 — WNT6
Text-mined interactions from Literome
Stewart et al., J Biol Chem 2000
:
These results indicate that the level of
cadherin-6 , but not that of E-cadherin, is strictly regulated post-translationally in
response to
Wnt signaling, and that E-cadherin and cadherin-6 may contribute different properties to cell-cell adhesion and the epithelial phenotype
Ohira et al., Proc Natl Acad Sci U S A 2003
(Lung Neoplasms) :
Drosophila
DE-cadherin is
regulated by
Wnt/beta-catenin signaling, although this has not been demonstrated in mammalian cells
Brembeck et al., Genes Dev 2004
:
beta-Catenin controls both
cadherin mediated cell adhesion and activation of
Wnt target genes
Obara et al., Methods Mol Biol 2006
(Cell Transformation, Neoplastic) :
beta-catenin seems to link
cadherin mediated cell-cell adhesion and
Wnt signaling
Sarrió et al., Hum Pathol 2006
(Adenocarcinoma...) :
Alterations in the
cadherin-catenin expression and
activation of the
Wnt signaling have been related to the pathology of ovarian carcinomas
Kreslova et al., Genesis 2007
(Choristoma...) :
beta-Catenin plays a key role in
cadherin mediated cell adhesion as well as in canonical
Wnt signaling
Haÿ et al., Mol Cell Biol 2009
:
These data indicate that a previously unrecognized
N-cadherin-axin-LRP5 interaction negatively
regulates Wnt/beta-catenin signaling and is critical in the regulation of osteoblast function, bone formation, and bone mass
Heuberger et al., Cold Spring Harbor perspectives in biology 2010
:
Interplay of
cadherin mediated cell adhesion and canonical
Wnt signaling ... beta-Catenin is an essential molecule both in
cadherin mediated cell adhesion and in canonical
Wnt signaling
Chalpe et al., Cell Adh Migr 2010
:
This project was initiated to investigate the
role of canonical
Wnt signaling in the expression of
cadherin-7 and cadherin-11 by treating neural crest cells with Wnt3a ligand
Xu et al., J Biol Chem 2011
:
To further explore the molecular mechanism of this regulation, the roles of ß-catenin, an essential molecule in both
cadherin mediated cell adhesion and canonical
Wnt signaling, were investigated
Howard et al., PloS one 2011
(Wnt Signaling Pathway) :
A positive
role of
cadherin in
Wnt/ß-catenin signalling during epithelial-mesenchymal transition
Haÿ et al., J Bone Miner Res 2012
(Wnt Signaling Pathway) :
Peptide based mediated disruption of
N-cadherin-LRP5/6 interaction
promotes Wnt signaling and bone formation ... We also show that the peptide mediated disruption of
N-cadherin-LRP5/6 interaction
increases Wnt/ß-catenin signaling and osteoblast function in vitro and promotes calvaria bone formation in vivo
Sengupta et al., J Cell Sci 2013
:
Transfection of hypoglycosylated E-cadherin mutant, V13, but not fully N-glycosylated
E-cadherin , into sparse cells
inhibited canonical
Wnt activity by depleting nuclear ß- and ?-catenins
Hadeball et al., Mech Dev 1998
:
Xenopus
cadherin-11 ( Xcadherin-11 ) expression
requires the
Wg/Wnt signal