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ANG — CRK
Text-mined interactions from Literome
Yoshizumi et al., Biochem Biophys Res Commun 2002
(MAP Kinase Signaling System) :
Ang II
activated extracellular signal regulated kinase ( ERK ) 1/2, JNK, and
p38 in RASMC
Su et al., Kidney Int 2006
:
While incubation of proximal tubular cells with Ang- ( 1-7 ) alone did not significantly affect MAPK phosphorylation,
Ang- ( 1-7 ) ( 10 ( -7 ) M ) completely
inhibited Ang II-stimulated phosphorylation of
p38 , ERK 1/2, and JNK
Won et al., Exp Mol Med 2006
:
Ang II
increases the phosphorylation of the extracellular signal regulated protein kinase 1/2 ( ERK 1/2 ), c-jun-N-terminal kinase 1/2 ( JNK 1/2 ), or
p38 mitogen activated protein kinases ( MAPKs ) and mRNA expression of c-jun and c-fos
Guo et al., Peptides 2006
(MAP Kinase Signaling System) :
Furthermore, AT(1) is required for
p38MAPK phosphorylation
induced by
Ang II
Zimpelmann et al., American journal of physiology. Renal physiology 2009
(MAP Kinase Signaling System) :
In proximal tubular cells,
Ang- ( 1-7 )
inhibits ANG II-stimulated phosphorylation of the mitogen activated protein kinases ( MAPKs )
p38 , extracellular signal related kinase ( ERK1/ERK2 ), and c-jun N-terminal kinase ( JNK ), suggesting that Ang- ( 1-7 ) protects against ANG II-mediated tubulointerstitial injury