UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to CRK

CRK — SORBS1

Pathways - manually collected, often from reviews:

NCI Pathway Database Insulin Pathway: TC10/GDP complex (RHOQ) → CBL/APS/CAP/Crk-II/C3G complex (CBL-SH2B2-CRK-SORBS1-RAPGEF1) (modification, collaborate)
Chiang et al., Nature 2001, Watson et al., J Cell Biol 2001, Chiang et al., J Biol Chem 2002
Evidence: mutant phenotype, assay
NCI Pathway Database Insulin Pathway: CBL/APS/CAP/Crk-II/C3G complex (CBL-SH2B2-CRK-SORBS1-RAPGEF1) → TC10/GTP complex (RHOQ) (modification, activates) Chiang et al., Nature 2001, Watson et al., J Cell Biol 2001, Chiang et al., J Biol Chem 2002
Evidence: mutant phenotype, assay
NCI Pathway Database Insulin Pathway: CBL/APS/CAP/Crk-II complex (CBL-SH2B2-CRK-SORBS1) → CBL/APS/CAP complex (CBL-SH2B2-SORBS1) (modification, collaborate)
Liu et al., Mol Cell Biol 2002, Ribon et al., Mol Cell Biol 1996
NCI Pathway Database Insulin Pathway: CBL/APS/CAP/Crk-II complex (CBL-SH2B2-CRK-SORBS1) → CRK-II (CRK) (modification, collaborate) Liu et al., Mol Cell Biol 2002, Ribon et al., Mol Cell Biol 1996
NCI Pathway Database Insulin Pathway: CBL/APS/CAP complex (CBL-SH2B2-SORBS1) → CRK-II (CRK) (modification, collaborate) Liu et al., Mol Cell Biol 2002, Ribon et al., Mol Cell Biol 1996
NCI Pathway Database Insulin Pathway: C3G (RAPGEF1) → CBL/APS/CAP/Crk-II complex (CBL-SH2B2-CRK-SORBS1) (modification, collaborate)
Ribon et al., Mol Cell Biol 1996
NCI Pathway Database Insulin Pathway: C3G (RAPGEF1) → CBL/APS/CAP/Crk-II/C3G complex (CBL-SH2B2-CRK-SORBS1-RAPGEF1) (modification, collaborate)
Ribon et al., Mol Cell Biol 1996
NCI Pathway Database Insulin Pathway: CBL/APS/CAP/Crk-II complex (CBL-SH2B2-CRK-SORBS1) → CBL/APS/CAP/Crk-II/C3G complex (CBL-SH2B2-CRK-SORBS1-RAPGEF1) (modification, collaborate)
Ribon et al., Mol Cell Biol 1996