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CRK — TLR4
Text-mined interactions from Literome
An et al., Immunology 2002
:
Involvement of ERK,
p38 and NF-kappaB signal transduction in regulation of TLR2,
TLR4 and TLR9 gene expression induced by lipopolysaccharide in mouse dendritic cells
Goral et al., J Immunol 2005
(Inflammation) :
Acute ethanol treatment inhibited IL-6 and TNF-alpha synthesis and impaired
p38 and ERK1/2 activation
induced by TLR2,
TLR4 , and TLR9 ligands
Maloney et al., J Biol Chem 2005
(MAP Kinase Signaling System) :
Here, we show that A52R does not inhibit
TLR induced
p38 or c-Jun amino N-terminal kinase (JNK) mitogen activating protein ( MAP ) kinase activation
Csóka et al., Blood 2007
:
The stimulatory effect of adenosine on E coli induced IL-10 production did not require
toll-like receptor 4 (TLR4) or MyD88, but was
blocked by
p38 inhibition
Hashimoto et al., J Cardiovasc Pharmacol 2009
:
TLR4 activation
increased phosphorylation of
p38 mitogen activated protein kinase and decreased production of prothrombotic phosphatidylserine and P-selectin positive microparticles in response to TRAP
Zhang et al., J Neuroimmunol 2010
:
In LPS treated primary SCs, retreatment with PPAR-gamma agonist remitted the increase of iNOS,
p38 phosphorylation and
TLR4 , MyD88,
augmented the expression of PPAR-gamma and localization in nuclear
Xia et al., J Pineal Res 2012
(Inflammation) :
Although it had no effect on
TLR4 mediated phosphorylation of c-Jun N-terminal kinase (JNK),
p38 , and extracellular regulated protein kinase ( ERK ), melatonin significantly attenuated the activation of nuclear factor kappa B ( NF-?B ) in LPS stimulated macrophages
Liu et al., PloS one 2012
(Shock, Septic) :
Moreover, DCO-6 specifically inhibited
TLR4 dependent
p38 activation without directly inhibiting its kinase activity