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RBMX — TXNIP
Text-mined interactions from Literome
Shin et al., Clin Cancer Res 2006
(Carcinoma, Squamous Cell...) :
In addition,
hnRNP G overexpression
led to up-regulation of the expression of
TXNIP , a cell cycle inhibitory gene, and significantly reduced the expression of the genes that promote cellular proliferation, such as EGR1, JUND, JUNB, FOS, FOSL1, ROS, and KIT
Shin et al., Biochem Biophys Res Commun 2008
:
Wt
hnRNP G binds and
transactivates the
Txnip promoter in vivo, whereas the K22R mutant does not ... These studies indicate that
hnRNP G promotes the expression of
Txnip and mediates its tumor-suppressive effect