Gene interactions and pathways from curated databases and text-mining

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TLR9 — TREM2

Text-mined interactions from Literome

Watarai et al., Proc Natl Acad Sci U S A 2008 : Thus, PDC-TREM is responsible for IFN-alpha production, whereas TLR signals are essential for PDC-TREM expression
Ito et al., Eur J Immunol 2012 : TREM-2 , triggering receptor expressed on myeloid cell-2, negatively regulates TLR responses in dendritic cells
Paradowska-Gorycka et al., Hum Immunol 2013 : Depending on the cell type, DAP12/TREM-2 activation plays an important role in activation and differentiation of osteoclasts, phagocytosis of bacteria, brain and bone homeostasis and inhibition of the toll-like receptor ( TLR ) signaling in macrophages and dendritic cells