Gene interactions and pathways from curated databases and text-mining

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TDG — XPC

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Shimizu et al., EMBO J 2003 (Xeroderma Pigmentosum) : XPC-HR23B stimulated TDG activity by promoting the release of TDG from abasic sites that result from the excision of mismatched T bases
Shimizu et al., Journal of nucleic acids 2010 : On the contrary, XPC significantly stimulates the activities of sumoylated TDG and SMUG1, both of which exhibit quite different enzymatic kinetics from unmodified TDG but interact with XPC