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CD2 — MAPK13
Text-mined interactions from Literome
Kefaloyianni et al., J Exp Biol 2005
(Heat Stress Disorders) :
In gills, both Cu2+ and Zn2+
induced a considerably higher
p38-MAPK activation, which remained elevated for at least 60 min, whereas
Cd2+ induced a maximal kinase activation within 60 min of treatment
Rigon et al., Neurotoxicology 2008
:
Phosphorylation of p38 (
MAPK ) was
enhanced by
Cd(II) at all doses tested
Templeton et al., Toxicol Lett 1998
:
Although Cd2+ has been reported to activate PKC in vitro, no effect was found on PKC activity in Cd2+ -treated cells, indicating the
activation of
MAPK by
Cd2+ is through an unidentified PKC independent pathway ... We conclude that
Cd2+ can
cause a sustained induction of c-fos in part through sustained activation of
MAPK , that contrasts with the transient activation of these species in response to physiological mitogenic stimuli