Gene interactions and pathways from curated databases and text-mining

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BMP3 — FGF13

Text-mined interactions from Literome

Xu et al., Cell stem cell 2008 : Using a defined medium, we show here that both TGFbeta and FGF signals synergize to inhibit BMP signaling ; sustain expression of pluripotency associated genes such as NANOG, OCT4, and SOX2 ; and promote long-term undifferentiated proliferation of human ESCs
Boswell et al., Dev Biol 2008 : Although BMP signaling is required for FGF to enhance fiber differentiation, the converse is not true
Lee et al., Biochim Biophys Acta 2009 : This process requires, at least in part, the inhibition of BMP signalling in the ectoderm by noggin, as well as FGF receptor activation and Ca2+ signalling
Huang et al., Development 2009 : FGF regulated BMP signaling is required for eyelid closure and to specify conjunctival epithelial cell fate
Mackem et al., Science signaling 2009 : In turn, SHH activity maintains the expression of Gremlin1, which encodes a bone morphogenetic protein ( BMP ) antagonist ; the interaction between BMP and Gremlin1 regulates Fgf gene expression
Tirosh-Finkel et al., Development 2010 : BMP mediated inhibition of FGF signaling promotes cardiomyocyte differentiation of anterior heart field progenitors
Yardley et al., Dev Biol 2012 : Finally, we report that prior to the upregulation of these neural crest markers, the non-neural ectoderm upregulates both BMP and Wnt molecules in response to FGF
Lupo et al., Open biology 2013 : We show that either BMP inhibition or activation of FGF signalling is required for effective neural induction, but these two pathways have distinct outcomes on rostrocaudal patterning