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IL8 — NOS2
Text-mined interactions from Literome
Galley et al., Crit Care Med 1999
(Shock, Septic) :
To determine the
effect of the
nitric oxide synthase inhibitor, L-N ( G ) -monomethylarginine, on interleukin-6 and
interleukin-8 accumulation, and nuclear factor-kappaB expression in an endothelial cell model of sepsis
Heitmeier et al., J Biol Chem 1999
(Insulinoma) :
Prolonged STAT1 activation is associated with interferon-gamma priming for
interleukin-1 induced inducible
nitric-oxide synthase expression by islets of Langerhans
Nédélec et al., Biochem Pharmacol 2001
:
In monolayers,
interleukin-1beta (IL-1beta)
induced COX-2 and
NOS II expression in a dose- and time dependent manner, to produce high prostaglandin E ( 2 ) ( PGE ( 2 ) ) and nitrite ( NO ( 2 ) ( - ) ) levels in an apparently coordinated fashion
Knuefermann et al., Circulation 2002
(Inflammation...) :
Myocardial tumor necrosis factor,
interleukin-1beta (IL-1beta), and
NOS2 induction was measured before and 6 hours after LPS challenge
Xiong et al., J Biol Chem 2003
:
In addition,
interleukin-4 inhibits IFN-gamma induced
iNOS gene expression by attenuating the physical interaction of ICSBP with IRF-1
Miljkovic et al., Cell Mol Life Sci 2003
:
The
role of
interleukin-17 in inducible
nitric oxide synthase mediated nitric oxide production in endothelial cells
Cattaruzza et al., J Biol Chem 2003
:
Interleukin-10 induction of
nitric-oxide synthase expression
attenuates CD40 mediated
interleukin-12 synthesis in human endothelial cells
McCall et al., Biochem Biophys Res Commun 1992
:
Interleukin-8 inhibits the induction of
nitric oxide synthase in rat peritoneal neutrophils ... The
effect of
interleukin(IL)-8 and leukotriene B4 (LTB4) on the induction of
nitric oxide ( NO ) synthase in rat peritoneal neutrophils ( PMN ) ex vivo was studied
Miljkovic et al., Cytokine Growth Factor Rev 2004
(Inflammation...) :
Inducible
nitric oxide synthase activation by
interleukin-17
Lee et al., Exp Cell Res 2004
(Bone Resorption) :
In this study, we found that TNF-alpha, but not receptor activator of nuclear factor kappa B ligand and
interleukin 1,
increased the expression of
iNOS both at the mRNA and protein levels
Davis et al., Alcohol 2004
:
Results from a previous study in our laboratory, in the human A172 astroglial cell line, revealed that
induction of
iNOS activity by tumor necrosis factor-alpha + interferon-gamma
+ interleukin-1 beta was inhibited by 24-h exposure to a high ethanol concentration ( 200 mM ), but enhanced by 50 mM ethanol
Look et al., J Immunol 2005
:
The thiol antioxidant N-acetyl cysteine, extracellular catalase, and
inducible NO synthase inhibitors
inhibited ICAM-1 and
IL-8 increases in response to both phenazines
Zheng et al., J Biol Chem 2006
(Bone Resorption) :
Using murine RAW 264.7 and primary bone marrow cells or osteoclasts formed from them by receptor activator of NF-kappaB ligand ( RANKL ) differentiation, we found that
inducible nitric-oxide synthase (iNOS) expression and NO generation were
stimulated by interferon (IFN)-gamma or lipopolysaccharide, but not by
interleukin-1 or tumor necrosis factor-alpha
Xu et al., Biochem Biophys Res Commun 2011
(Cardiovascular Diseases...) :
Knock-down of RSK1 selectively down regulated
interleukin-1ß induced
iNOS expression without influencing VCAM-1 expression
Cho et al., J Nutr Biochem 2012
:
Effects of physiological quercetin metabolites on
interleukin-1ß induced
inducible NOS expression
Seo et al., Immunopharmacol Immunotoxicol 2012
(Inflammation) :
SPEE treatment significantly inhibited the LPS induced production of NO, prostaglandin E ( 2 ),
interleukin-6 , and tumor necrosis factor-a and
inhibited the expression of
iNOS and COX-2 via attenuation of NF-?B p65 expression
Singh et al., J Biol Chem 1995
:
In vitro,
interleukin-1 beta and interferon-gamma
increased osteopontin mRNA levels in CMEC as well as
NOS2 expression in both CMEC and cardiac myocytes
Szabó et al., Eur J Pharmacol 1993
:
We investigated the
role of
interleukin-1 in the induction of a Ca ( 2+ ) -independent
nitric oxide ( NO ) synthase by bacterial endotoxin in vivo
Tetsuka et al., Proc Natl Acad Sci U S A 1994
:
Cross-talk between cyclooxygenase and nitric oxide pathways : prostaglandin E2 negatively modulates
induction of
nitric oxide synthase by
interleukin 1
Andrew et al., Biochem Biophys Res Commun 1995
(Melanoma) :
The
nitric oxide synthase inhibitor, NG-amino-L-homoarginine ( NAHA ),
inhibited TNF-alpha stimulated
IL-8 promoter activity by 60 %
Kanno et al., Hypertension 1993
:
Induction of
nitric oxide synthase gene by
interleukin in vascular smooth muscle cells
Flak et al., Am J Respir Crit Care Med 1996
(Asthma...) :
The induction of
iNOS is most likely
due to the cytokine
interleukin-1 , which is generated intracellularly in response to TCT ; this cytokine, like TCT, can reproduce the pathology caused by B. pertussis infection
Heitmeier et al., J Biol Chem 1997
:
Interferon-gamma increases the sensitivity of islets of Langerhans for inducible
nitric-oxide synthase expression
induced by
interleukin 1
Kinugawa et al., Circ Res 1997
:
Forskolin,
interleukin (IL)-6 , tumor necrosis factor (TNF)-alpha, or interferon (IFN)-gamma
enhanced the LPS induced
iNOS expression