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NOS2 — REL
Text-mined interactions from Literome
Weidenbach et al., J Hepatol 2000
(Colitis...) :
Although low levels of portal endotoxin were measured during the first 2 days of colitis, no significant
NF-kappaB/Rel activity and
NOS2 induction were detected in the liver
Kang et al., J Pharmacol Exp Ther 2002
:
Collectively, these results suggest that silymarin
inhibits nitric oxide production and
iNOS gene expression by inhibiting
NF-kappaB/Rel activation
Jeon et al., J Ethnopharmacol 2006
:
KIOM-79
inhibits LPS induced
iNOS gene expression by blocking
NF-kappaB/Rel and p38 kinase activation in murine macrophages ... Collectively, this series of experiments indicates that KIOM
inhibits iNOS gene expression by blocking
NF-kappa/Rel and p38 kinase signaling
Cieslik et al., Mol Pharmacol 2006
:
Essential
role of
C-Rel in
nitric-oxide synthase-2 transcriptional activation : time dependent control by salicylate
Li et al., The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2010
:
This study demonstrates the ability of magnolol, a hydroxylated biphenyl compound isolated from Magnolia officinalis, to inhibit LPS induced expression of
iNOS gene and
activation of
NF-?B/Rel in RAW 264.7 cells ... Collectively, the results of the series of experiments indicate that magnolol
inhibits iNOS gene expression by blocking
NF-?B/Rel and p38 kinase signaling
Hwang et al., Nitric Oxide 2013
:
Glucosamine
inhibits lipopolysaccharide stimulated inducible
nitric oxide synthase induction by inhibiting expression of
NF-kappaB/Rel proteins at the mRNA and protein levels ... We show that GlcN selectively
inhibits sustained
iNOS induction by inhibiting
Rel protein expression at both the mRNA and protein levels ; such expression is required for prolonged iNOS induction by LPS
Xie et al., J Biol Chem 1994
:
Role of transcription factor NF-kappa
B/Rel in induction of
nitric oxide synthase