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IGFBP1 — MTOR
Text-mined interactions from Literome
Patel et al., J Biol Chem 2002
:
We propose that these observations indicate that an
mTOR dependent, but S6K independent mechanism
regulates the suppression of
IGFBP-1 ( but not G6Pase ) gene expression by insulin
Patel et al., Biochem J 2002
:
Our results support the view that the insulin mediated repression of
IGFBP-1 gene expression is partly
mTOR dependent , and demonstrate that H ( 2 ) O ( 2 ) selectively antagonizes mTOR dependent insulin action
Mounier et al., Endocrinology 2006
:
In confluent hepatocytes, insulin could not activate the phosphatidylinositol 3-kinase ( PI3 kinase ) -Akt-Foxo1/Foxo3 pathway, but still inhibited
IGFBP-1 gene expression in an
mTOR dependent manner