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ADCY8 — IL12B
Text-mined interactions from Literome
Liu et al., Immunology 2000
:
The LPS induced
IL-12 release from Mphi could also be
reduced by forskolin, an activator of
adenylate cyclase , and 8-Br-cAMP, an analogue of cAMP
Panther et al., FASEB J 2001
:
However, in LPS differentiated DCs, adenosine and an A ( 2a ) receptor agonist stimulated
adenylate cyclase activity, enhanced intracellular cAMP levels, and
inhibited interleukin 12 (IL-12) production
Skinner et al., J Immunol 2004
(Bordetella Infections...) :
The B. bronchiseptica type III secretion system ( TTSS ) mediated the increase in MHCII, CD86, and CD80 surface expression, while the inhibition of CD40 and
IL-12 expression was
mediated by
adenylate cyclase toxin ( ACT )