◀ Back to IL12B

CD86 — IL12B

Text-mined interactions from Literome

Foss et al., Infect Immun 1999 : LPS and CT each induced IL-1beta expression in macrophages, while only LPS induced IL-12 and only CT induced CD80-CD86
Satthaporn et al., Cancer Immunol Immunother 2004 (Breast Neoplasms) : PBDCs and LNDCs from patients expressed low levels of HLA-DR and CD86 , and induced decreased interleukin-12 (IL-12) secretion in vitro, compared with DCs from normal donors ( p < 0.01 )
Pedraza-Sánchez et al., Int Immunopharmacol 2006 : The early activation marker CD69 was induced at 4 h in NK cells > B cells > T cells > monocytes whereas at 24 h CD80 and CD86 levels were augmented on monocytes and IL-12 was induced ; HLA-DR levels increased on both B cells and monocytes
Yoon et al., Mol Pharmacol 2006 : In the presence of apigenin, CD80, CD86 , and major histocompatibility complex class I and II molecules, expressions on DC were significantly suppressed, and lipopolysaccharide (LPS) induced interleukin (IL)-12 expression was impaired
Shi et al., Arch Dermatol Res 2007 : We demonstrate that after treatment with PS, murine DCs display reduced expression of MHC II, CD80, CD86 and CD40, but increased programmed death ligand-1 ( PD-L1 and PD-L2 ) ; and increased IL-10 and inhibited IL-12 cytokine production
Steers et al., Vaccine 2008 : L ( LA ) enhanced the surface expression of MHC class I, class II, CD80, and CD86 molecules, induced the secretion of IFN-gamma, IL-12p40 , TNF-alpha and IL-10, and caused a shift in the proteasome profile from constitutive to immunoproteasomes as observed by the induction of beta2i, beta5i, PA28alpha, and PA28beta subunits
Chen et al., Immunol Lett 2012 (Liver Neoplasms...) : We found that Tregs derived from the tumor mice down-regulated the expression of costimulatory molecules CD80/CD86 on DCs and inhibited the production of TNF-a and IL-12 from DCs
Xue et al., Int Immunopharmacol 2013 : We elucidated that IFN-? up-regulated the expression of MHC II, CD40, CD80, CD83 and CD86 molecules on BMDCs, down-regulated the activity of pinocytosis and phagocytosis by BMDCs, and induced higher levels of IL-12 and TNF-a secreted by BMDCs
Suemoto et al., J Dermatol Sci 1998 : The expression of MHC class II, CD80 and CD86 on EC was not affected by IL-12