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BCAP31 — CASP9
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Chandra et al., Mol Cell Biol 2004
:
Finally, we present evidence that the OMM localized active
caspase 8 can
activate cytosolic caspase 3 and ER-localized
BAP31
Panaretakis et al., EMBO J 2009
:
Early activation of the endoplasmic reticulum ( ER ) -sessile kinase PERK leads to phosphorylation of the translation initiation factor eIF2alpha, followed by partial activation of caspase-8 ( but not caspase-3 ),
caspase-8 mediated cleavage of the ER protein
BAP31 and conformational activation of Bax and Bak