UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to MTOR

EIF3F — MTOR

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

IRef Biogrid Interaction: EIF3F — MTOR (physical association, affinity chromatography technology) Harris et al., EMBO J 2006 *
IRef Biogrid Interaction: EIF3F — MTOR (direct interaction, two hybrid) Harris et al., EMBO J 2006 *
IRef Hprd Interaction: EIF3F — MTOR (two hybrid) Harris et al., EMBO J 2006 *
IRef Hprd Interaction: EIF3F — MTOR (in vitro) Harris et al., EMBO J 2006 *

Text-mined interactions from Literome

Harris et al., EMBO J 2006 : mTOR dependent stimulation of the association of eIF4G and eIF3 by insulin ... Here, we present evidence that mTOR interacts directly with eIF3 and that mTOR controls the association of eIF3 and eIF4G ... This novel effect was blocked by rapamycin and other inhibitors of mTOR , and it required neither eIF4E binding to eIF4G nor eIF3 binding to the 40S ribosomal subunit
Csibi et al., PloS one 2010 : The translation regulatory subunit eIF3f controls the kinase dependent mTOR signaling required for muscle differentiation and hypertrophy in mouse