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AKT1 — NPPA
Text-mined interactions from Literome
Kook et al., Am J Physiol Heart Circ Physiol 2003
:
ANP increased the expression of
phospho-Akt and of phospho-ERK1/2 within 1.5 h
Ladetzki-Baehs et al., Endocrinology 2007
(Inflammation) :
ANP also
reduces Akt activation upon lipopolysaccharide injection
You et al., Endocrinology 2009
:
ANP and 8-Br-cGMP
stimulated the phosphorylation of
Akt and Foxo1a in INS-1E cells and islets, and LY294002 inhibited these responses ... These data support the conclusion that the
activation of
Akt by
ANP or 8-Br-cGMP promotes cyclin D2, PDX-1, and glucokinase transcription by phosphorylating and restricting Foxo1a activity
Sauvé et al., Diabetes 2010
(Diabetes Mellitus, Experimental...) :
Increased cardiac expression of phosphorylated
AKT ( pAKT ), pGSK3beta, and atrial natriuretic peptide (ANP) was detected in the nonischemic Dpp4 ( -/- ) heart, and HO-1,
ANP , and pGSK3beta proteins were
induced in nonischemic hearts from diabetic mice treated with sitagliptin or metformin
O'Tierney et al., J Physiol 2010
:
Ang II-stimulated ERK and
Akt phosphorylation was
inhibited by 100 nm
ANP
Nesher et al., Can J Physiol Pharmacol 2012
:
Furthermore, ouabain ( 50 nmol/L ) or
ANP ( 10 nmol/L ) alone
induced Akt activation in cardiomyocytes ... However,
ANP blocked ouabain induced
Akt activation