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CCND1 — NEUROD1

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: NEUROD1 → CCND1 (directlyDecreases, CCND1 Activity)
  Evidence: Previous studies have demonstrated a role for cyclin D1 in the repression of several distinct transcription factors (Fig. 4). In addition to binding CDK4, CDK6, and pRB, cyclin D1 forms physical associations with P/CAF (p300/CB P associated factor), Myb, MyoD, and the cyclin D1 myb-like binding protein (DMP1) [8-11]. Cyclin D1 and D2 are capable of inhibiting MyoD [12]. v-Myb is preferentially repressed by cyclin D1 [9], although cyclin D2 and D3 are also capable of repressing v-Myb; the helix-l...

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: NEUROD1 — CCND1 (physical association, affinity chromatography technology) Ratineau et al., J Biol Chem 2002*
• MIPS CORUM BETA2-Cyclin D1 complex: BETA2-Cyclin D1 complex complex (CCND1-NEUROD1) Ratineau et al., J Biol Chem 2002*
• IRef Corum Interaction: NEUROD1 — CCND1 (association, coimmunoprecipitation) Ratineau et al., J Biol Chem 2002*
• IRef Hprd Interaction: Complex of 19 proteins (in vivo) Ratineau et al., J Biol Chem 2002*