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CASP5 — ERVK-6

Text-mined interactions from Literome

Wolf et al., Blood 1999 : Supporting this, inhibition of the calcium dependent proteinase , calpain, prevented caspase proteolysis, ` apoptotic ' substrate cleavage, and platelet microvesiculation
Suzuki et al., Exp Cell Res 1997 : The results showed that Fas mediated apoptosis was accompanied by caspase 3 activation, and both Fas mediated apoptosis and caspase 3 activation were prevented by a serine proteinase inhibitor ... In addition, the serine proteinase inhibitor also prevented the caspase 3 activation in cytoplasts, and the specific activation of serineproteinase was encountered in only cytoplasmic proteins ... These results strongly suggest that a cytoplasmic S. aureus V8-like serine proteinase is closely involved in caspase 3 activation