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GPR22 — VEGFA

Text-mined interactions from Literome

Montaner et al., Cancer Res 2001 (Cell Transformation, Viral) : Here, we describe that this constitutively active G protein coupled receptor is able to promote cell survival in primary human umbilical vein endothelial cells and that this effect is independent of its ability to secrete VEGF because it is not prevented by the expression of antisense constructs for VEGF or the addition of VEGF blocking antibodies
Jham et al., PloS one 2011 (Inflammation...) : Here we report that the KSHV G protein coupled receptor ( vGPCR ) upregulates VEGF in KS through an intricate paracrine mechanism
Yang et al., Cancer Res 2011 (Melanoma...) : We report that a novel G protein coupled receptor , GPR56, inhibits VEGF production from the melanoma cell lines and impedes melanoma angiogenesis and growth, through the serine threonine proline-rich segment in its N-terminus and a signaling pathway involving protein kinase Ca
Masiero et al., Cancer Cell 2013 (Genetic Predisposition to Disease...) : This approach identified ELTD1, an orphan G-protein coupled receptor whose expression is induced by VEGF/bFGF and repressed by DLL4 signaling