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MAP3K11 — MAPK3

Pathways - manually collected, often from reviews:

• NCI Pathway Database IFN-gamma pathway: Erk1-2-active (MAPK3/MAPK1) → MAP3K11 (MAP3K11) (modification, activates) Hu et al., J Biol Chem 2001, Roy et al., Proc Natl Acad Sci U S A 2002, Roy et al., J Biol Chem 2005
  Evidence: mutant phenotype

Text-mined interactions from Literome

Korchnak et al., Cell Signal 2009 : Mixed lineage kinase 3 (MLK3) is a mitogen activated protein kinase kinase kinase ( MAP3K ) that activates multiple mitogen activated protein kinase ( MAPK ) pathways in response to growth factors, stresses and the pro-inflammatory cytokine, tumor necrosis factor (TNF)
López-Pelaéz et al., Mol Biol Cell 2012 (Inflammation...) : Cot/tpl2 is the only MAP3K that activates MKK1/2-Erk1/2 in Toll-like receptor activated macrophages
Amako et al., J Biol Chem 2013 (Hepatitis C) : MLK3 is a serine/threonine protein kinase that is a member of the MAPK kinase kinase ( MAP3K ) family and activates p38MAPK