◀ Back to MAPK14
CXADR — MAPK14
Text-mined interactions from Literome
Tfelt-Hansen et al., Endocrinology 2004
(Hypercalcemia...) :
Taken together, our data show that
activation of PI3K and p38
MAPK but not of MEK1/ERK by the
CaR promotes proliferation of H-500 cells as well as affords protection against apoptosis
Ye et al., J Neurosci Res 2004
:
The effect of high Ca2+ ( o ) on p38
MAPK but not ERK1/2 is
CaR mediated , insofar as transduction with a dominant negative CaR ( R185Q ) using recombinant adeno associated virus ( rAAV ) attenuated the activation of p38 MAPK but not of ERK1/2 ... p38
MAPK activation by the
CaR is likely to be protein kinase C ( PKC ) independent, in that the pan-PKC inhibitor GF109203X failed to abolish the high-Ca2+ ( o ) -induced phosphorylation of p38 MAPK
Gray et al., J Endocrinol 2006
:
CaR activation was also associated with an activation of p42/44 mitogen activated protein kinases ( MAPK ), and CaR induced insulin secretion was
reduced by an inhibitor of p42/44
MAPK activation