◀ Back to MAPK14
DUSP6 — MAPK14
Pathways - manually collected, often from reviews:
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Reffas et al., Biochem J 2000
:
Activation of mitogen activated protein kinases ( MAPKs ), their upstream activators
MAPK kinases ( MAPKKs or MEKs ) and
induction of MKP-1 ( CL100/3CH134 ) and
MKP-3 ( Pyst1/rVH6 ) dual-specificity MAPK phosphatases ( MKPs ) were studied in the mouse embryonic stem cell line P19 during the 7 day induction of neuronal differentiation triggered by aggregation and retinoic acid
Givant-Horwitz et al., Gynecol Oncol 2004
(MAP Kinase Signaling System...) :
The objective of the present study was to investigate the expression and clinical role of
dual-specificity phosphatases ( DUSP ) ,
inhibitors of
MAPK signaling, in ovarian cancer cells at this site
Cui et al., Cancer Res 2006
(Breast Neoplasms) :
Furthermore, PD98059 increased the levels of phosphorylated c-Jun NH ( 2 ) -terminal kinase ( JNK ) in tamoxifen treated MKP3 overexpressing cells, suggesting an interaction between
MKP3 levels,
activation of ERK1/2
MAPK , and JNK signaling in human breast cancer cells
Kumabe et al., Microbiol Immunol 2010
:
Activation of
MAPK is negatively
regulated by
DUSP , which dephosphorylate the phosphothreonine and phosphotyrosine residues
Camps et al., Science 1998
:
Catalytic
activation of the phosphatase
MKP-3 by ERK2
mitogen activated protein kinase