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MAPK14 — MMP10
Text-mined interactions from Literome
Dai et al., Ann Rheum Dis 2005
(Arthritis...) :
In chondrocytes responding to IL18, IL18 ( 1-100 ng/ml ) slightly increased the production of MMP-1,
MMP-3 , and MMP-13, which was
blocked by NF-kappaB inhibitor and p38
mitogen activated protein kinase inhibitor
Song et al., Endocrinology 2007
(Breast Neoplasms) :
In noncancer cells, IGF-I initiates a linear process involving activation of the IGF-I receptor (IGF-IR) and
matrix metalloproteinases ( MMP ) , release of heparin binding epidermal growth factor ( HB-EGF ), and
activation of EGF receptor (EGFR) dependent
MAPK
d'Abusco et al., Arthritis Res Ther 2007
(MAP Kinase Signaling System) :
These findings demonstrate, for the first time, that glucosamine
inhibits IL-1beta stimulated
MMP production in human chondrocytes by affecting
MAPK phosphorylation
Uttamsingh et al., Oncogene 2008
(Cell Transformation, Neoplastic) :
Among them, the expression of MMP1, MMP3,
MMP9 and MMP10 was
MAPK dependent ... Among them, the expression of MMP1, MMP3, MMP9 and
MMP10 was
MAPK dependent
Ding et al., Osteoarthritis Cartilage 2008
:
To define the
role of
mitogen activated protein ( MAP ) kinases in fibronectin fragment ( Fn-f ) mediated
matrix metalloproteinase ( MMP ) upregulation and damage to bovine cartilage and to compare activities of three Fn-fs with native fibronectin ( Fn ), which is inactive in terms of cartilage damage
Santibáñez et al., FEBS Lett 2010
:
Furthermore,
MMP9 production was
MAPK dependent , as the MEK inhibitor PD98059 decreased TGF-beta1 induced MMP9 expression and secretion in Q61LRac1 expressing cells
Heo et al., J Cell Physiol 2010
:
The inhibition of PI3K and
MAPK inhibited VEGF induced
MMP-10 expression
Chen et al., Invest New Drugs 2011
(Breast Neoplasms) :
The
MAPK inhibitors effectively
prevented the loss of
MMP and apoptosis induced by protoapigenone
You et al., Mol Biol Rep 2011
:
All the
MAPK inhibitors slightly
enhanced cell growth inhibition, death and
MMP ( d?m ) loss, and increased ROS levels in PG-treated HeLa cells
Ruiz et al., J Biol Chem 2011
(MAP Kinase Signaling System) :
Furthermore, activation of DDR2, JAK2, and ERK1/2
MAPK signaling pathways was
essential for collagen I-induced DDR1 and
matrix metalloproteinase 10 expression
Cui et al., Biochem Biophys Res Commun 2012
(Neoplasm Invasiveness) :
Subsequent functional validation revealed that K63E and S193A mutants, which disrupted CD147 dimerization both in solution and in living cells, showed clearly dominant negative effects on
MAPK activation,
MMP2 induction and invasiveness in tumor cells
Lee et al., J Dermatol Sci 2013
:
In UVB irradiated HaCaT cells, 8-oxo-dG inhibited ROS production, subsequent
activation of
mitogen activated protein kinase ( MAPK ), ATF-2, and c-Jun, and
MMP expression