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IL4 — MED1
Text-mined interactions from Literome
Speziani et al., Eur J Immunol 2007
:
IL-2, IFN-gamma and
IL-4 inhibit
TRAP and bone resorption activities contrary to IL-10, which enhances both activities
Yu et al., J Biol Chem 2009
:
To determine whether
IL-4 regulates
TRAP promoter activity, RAW264.7 cells were transfected with a TRAP promoter-luciferase reporter ... Knockdown of NFATc1 by short interfering RNA caused TRAP expression to be down-regulated, and ectopic expression of NFATc1 abrogated the
IL-4 induced down-regulation of
TRAP
Kasono et al., Bone Miner 1993
(Bone Resorption) :
The minimum effective inhibitory concentration was 0.01 ng/ml, and 1 ng/ml
IL-4 completely
inhibited TRAP ( + ) MNC formation