Gene interactions and pathways from curated databases and text-mining

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AGTR1 — MMP7

Text-mined interactions from Literome

Li et al., Yao Xue Xue Bao 2003 (Ear Diseases...) : Gelatin zymography results showed that MMP-9 expression in U937 cells increased significantly after exposed to PMA at 1 x 10 ( -8 ) mol.L-1 ( P < 0.001 ) ; MMP-9 expression induced with phorbol myristate acetate ( PMA ) was inhibited by dexamethasone at 1 x 10 ( -9 ), 1 x 10 ( -7 ) and 1 x 10 ( -5 ) mol.L-1, indomethacin at 1 x 10 ( -6 ) and 1 x 10 ( -5 ) mol.L-1 and resveratrol at 1 x 10 ( -6 ) and 1 x 10 ( -5 ) mol.L-1
Akhavan et al., Pak J Biol Sci 2011 (Melanoma) : AT1 receptors activation enhances the expression of MMP-2, MMP-13 and VEGF but not MMP-9 in B16F10 melanoma cells
Piao et al., Chem Biol Interact 2013 (Necrosis) : In the present study, caspase dependent apoptosis was induced by SHK treatment at 1µM after 6h in U937 cells, with increase in DNA fragmentation, generation of intracellular reactive oxygen species ( ROS ), fraction of cells with low mitochondrial membrane potential ( MMP ) , and in the expression of BH3 only proteins Noxa and tBid