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POT1 — RAC3
Text-mined interactions from Literome
Maillet et al., Nat Cell Biol 2003
(Alzheimer Disease) :
We also show that
Rac activation
results from activation of
Rap1 through the cAMP guanine nucleotide-exchange factor (GEF) Epac1
Sato et al., Cancer Sci 2005
:
The activation of Cdc42 and
Rac by the trans-interaction of nectin and nectin is
mediated by c-Src, another small G protein,
Rap1 , a Cdc42-GEF, FRG, and a Rac-GEF, Vav2 ... The trans-interaction of Necl-5 and nectin-3 also activates
Rap1 through C3G, a Rap-GEF, and this activation of Rap1 is
required for the activation of Cdc42 and
Rac
Birukova et al., Exp Cell Res 2007
(Respiratory Distress Syndrome, Adult) :
Prostaglandins PGE ( 2 ) and PGI ( 2 ) promote endothelial barrier enhancement via PKA- and
Epac1/Rap1 dependent
Rac activation