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BCRP4 — TP53
Text-mined interactions from Literome
Wang et al., FEBS Lett 2010
:
Here, we investigate the
effects of wild-type and mutant
p53 , and nuclear factor kappa-B (NF-kappaB) ( p50 ) on
BCRP promoter activity in MCF-7 cells ... Our results demonstrated that wild-type
p53 markedly
suppressed BCRP activity and enhanced the chemosensitivity of cells to mitoxantrone, whereas mutant p53 had little inhibitory effect
Wang et al., Int J Biochem Cell Biol 2013
:
However, may be due to the physical interaction between p53 and Survivin,
p53 directly
affected Survivin regulated
BCRP expressions