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BMP4 — FGF12

Text-mined interactions from Literome

Wilson et al., Curr Biol 2000 : Fgf3 was also found to be expressed in the early epiblast, and ongoing FGF signalling in epiblast cells was required for acquisition of neural fate and for the suppression of Bmp4 and Bmp7 expression
Holleville et al., Dev Biol 2003 : In addition, FGF4 activates Bmp4 but not Bmp7 gene transcription and is not sufficient to induce ectopic Dlx5 expression in the immature calvarial mesenchyme
Bouhon et al., Brain Res Bull 2005 : Neural differentiation in CDM does not occur by a simple default mechanism, but was dependent on endogenous FGF signaling, and could be blocked by adding BMP4 , and LiCl to simulate WNT activation
Sperber et al., Dev Biol 2008 : FGF signaling is required for maintaining barx1 expression, and that ectopic BMP4 induces expression of barx1 in the intermediate region of the second pharyngeal arch
Xu et al., Cell stem cell 2008 : Using a defined medium, we show here that both TGFbeta and FGF signals synergize to inhibit BMP signaling ; sustain expression of pluripotency associated genes such as NANOG, OCT4, and SOX2 ; and promote long-term undifferentiated proliferation of human ESCs
Boswell et al., Dev Biol 2008 : Although BMP signaling is required for FGF to enhance fiber differentiation, the converse is not true
Lee et al., Biochim Biophys Acta 2009 : This process requires, at least in part, the inhibition of BMP signalling in the ectoderm by noggin, as well as FGF receptor activation and Ca2+ signalling
Maatouk et al., Dev Biol 2009 (Limb Deformities, Congenital) : At the molecular level, removal of Bmp2 and Bmp4 in the AER caused an increase in Fgf expression, which correlated with an increase in both the width and length of the AER
Hansson et al., Dev Biol 2009 : Additionally, we find a late dependence on FGF signaling during induction of Sox17 ( + ) cells by activin while BMP4 induced T expression requires FGF signaling in adherent but not aggregate culture
Huang et al., Development 2009 : FGF regulated BMP signaling is required for eyelid closure and to specify conjunctival epithelial cell fate
Mackem et al., Science signaling 2009 : In turn, SHH activity maintains the expression of Gremlin1, which encodes a bone morphogenetic protein ( BMP ) antagonist ; the interaction between BMP and Gremlin1 regulates Fgf gene expression
Zhang et al., Development 2010 : Mechanistic studies show that BMP4 inhibits FGF/ERK activity at the first stage but not at the second stage ; and IDs, as important downstream genes of BMP signaling, partially substitute for BMP4 functions at both stages
Tirosh-Finkel et al., Development 2010 : BMP mediated inhibition of FGF signaling promotes cardiomyocyte differentiation of anterior heart field progenitors
Yardley et al., Dev Biol 2012 : Finally, we report that prior to the upregulation of these neural crest markers, the non-neural ectoderm upregulates both BMP and Wnt molecules in response to FGF
Lupo et al., Open biology 2013 : We show that either BMP inhibition or activation of FGF signalling is required for effective neural induction, but these two pathways have distinct outcomes on rostrocaudal patterning