Gene interactions and pathways from curated databases and text-mining

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BMP4 — MAPK12

Text-mined interactions from Literome

Goswami et al., Dev Biol 2001 (MAP Kinase Signaling System) : We have examined the effects of BMP-4 on MAPK activity in gastrula ectoderm ... Our findings indicate that BMP-4 inhibits ectodermal MAPK activity through a TAK1/p38-type pathway
Viñals et al., FEBS Lett 2002 : In contrast, BMP-2 had no effect on p42/p44 MAPK ( Erks ) stimulation
Yang et al., Circ Res 2005 (Hypertension, Pulmonary) : These differences were not caused by differential activation of BMP signaling pathways because exogenous BMP-4 led to phosphorylation of Smad1, p38 ( MAPK ), and ERK1/2 in both cell types
Gotoh et al., Mol Cell Biol 2005 : In addition, experiments are presented demonstrating that Bmp4 expression in TS cells is controlled by mitogen activated protein kinase dependent FGF4 stimulation
Otani et al., American journal of physiology. Renal physiology 2007 : Antagonistic effects of bone morphogenetic protein-4 and -7 on renal mesangial cell proliferation induced by aldosterone through MAPK activation
Leong et al., PloS one 2009 (Osteoporosis) : These results indicate that protein palmitoylation plays an important role in BMP induced MAPK activation, osterix expression, and osteoblast differentiation
Park et al., Blood 2010 (Ischemia) : A higher proportion of CD34 ( + ) cells ( ~ 20 % ) could be derived from hPSCs by inhibition of mitogen activated protein kinase ( MAPK ) extracellular signal regulated protein kinase ( MEK ) /extracellular signal regulated kinase ( ERK ) signaling and activation of bone morphogenic protein-4 (BMP4) signaling. hPSC derived CD34 ( + ) progenitor cells further developed to endothelial and smooth muscle cells with functionality
Ge et al., J Bone Miner Res 2012 (MAP Kinase Signaling System) : Significantly, in the presence of AA, BMP2/7 synergistically stimulated RUNX2 S319 phosphorylation and transcriptional activity without affecting total RUNX2 and this response was totally dependent on ERK/MAPK activity
Ebeling et al., Reprod Fertil Dev 2011 : Furthermore, BMP-6 did not affect the activity of the mitogen activated protein kinase
Yumoto et al., J Biol Chem 2013 (Cleft Palate) : Our studies show that in neural crest derived craniofacial ecto-mesenchymal cells, Tak1 is not only required for TGF-ß- and bone morphogenetic protein induced p38 Mapk activation but also plays a role in agonist induced C-terminal and linker region phosphorylation of the receptor mediated R-Smads