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BMP4 — SHOX2

Text-mined interactions from Literome

Yu et al., Development 2005 (Cleft Palate) : BMP activity is necessary but not sufficient for the induction of palatal Shox2 expression
Puskaric et al., Hum Mol Genet 2010 : In addition, ectopic expression of Shox2 in Xenopus embryos stimulates transcription of the Bmp4 gene, and silencing of Shox2 in cardiomyocytes leads to a reduction in the expression of Bmp4 ... In Tbx5 ( del/+ ) mice, a model for Holt-Oram syndrome, and Shox2 ( -/- ) mice, we show that the T-box transcription factor Tbx5 is a regulator of Shox2 expression in the inflow tract and that Bmp4 is regulated by Shox2 in this compartment of the embryonic heart