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MDM2 — XIAP
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Gu et al., Cancer Cell 2009
(Neoplasms) :
Regulation of
XIAP translation and induction by
MDM2 following irradiation ... Herein we demonstrate that the upregulation of
XIAP protein levels is
regulated by
MDM2 at the translational level
Huang et al., Mol Cancer Ther 2013
:
Triptolide mediated downregulation of
MDM2 increased inhibition of
X-linked inhibitor of apoptosis protein ( XIAP ), its translational target, in a manner distinct from reactions to cellular stress and DNA damaging agent ionizing radiation that induce XIAP due to p53 activated MDM2