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NA — RNF19A

Text-mined interactions from Literome

Hashimoto et al., Am J Respir Crit Care Med 2000 : NAC inhibited DEP induced p38 MAP kinase activation and IL-8 and RANTES production
Chan et al., Am J Respir Cell Mol Biol 2001 (MAP Kinase Signaling System) : Here we show that in a serum depleted environment ( 0.1 % fetal bovine serum ), NAC substantially inhibited lipopolysaccharide (LPS) activation of the mitogen activated protein kinases ( MAPKs ), namely extracellular signal regulated kinase ( ERK ), p38mapk , and c-Jun NH2-terminal kinase (JNK)
Junn et al., J Neurochem 2001 (Neuroblastoma) : In addition, the antioxidant N-acetyl-L-cysteine (NAC) effectively blocks DA-induced p38 kinase activation, caspase-9 and caspase-3 cleavage and subsequent apoptosis, indicating that DA triggers apoptosis via a signaling pathway that is initiated by the generation of reactive oxygen species ( ROS )
Lin et al., J Neurosci Res 2006 : Unexpectedly, NAC also increased phosphorylated level of p38 mitogen activated protein kinase ( MAPK ) and p38 specific inhibitors dose-dependently attenuated the effect of NAC
Kang et al., J Cell Physiol 2008 (Uterine Cervical Neoplasms) : In addition, N-acetyl-L-cystein (NAC) , a thiol containing anti-oxidant, completely blocked As2O3 induced p38 MAPK and JNK activations, mitochondria translocation of Bax, and phosphorylation of Bcl-2
Sun et al., Biochem Pharmacol 2010 (MAP Kinase Signaling System...) : NAC subsequently inhibited BEL induced activation of p38 and p53 in LNCaP cells
Usui et al., J Pharmacol Sci 2010 (Atherosclerosis) : NAC inhibited TNF induced phosphorylation of JNK and p38 but not NF-kappaB