Gene interactions and pathways from curated databases and text-mining

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CAPN12 — INS

Text-mined interactions from Literome

Zhou et al., Metabolism 2003 : In summary, long-term inhibition of islet calpain activity attenuates insulin secretion possibly by limiting the rate of glucose metabolism
Kalbe et al., Br J Nutr 2005 (Disease Models, Animal...) : Lactacystin and calpain inhibitor I, but not isovaleryl-L-carnitine, raised insulin secretion in control islets, indicating that proteasome and cysteinyl cathepsin(s), but not mu-calpain , are involved in fetal insulin secretion
Leloup et al., Int J Biochem Cell Biol 2007 (MAP Kinase Signaling System) : The aim of this study was to identify the signalling pathway ( s ) responsible for the effects of IGF-1, TGF-beta1, and insulin on myoblast migration and on milli-calpain expression and activity