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ATF2 — CASP8

Text-mined interactions from Literome

Zebrowski et al., J Mol Cell Cardiol 2006 (Ischemia...) : In addition, caspase-3 inhibited the ability of the wild-type full-length form of MEKK1 to activate ATF2 , suggesting that caspase-3, by way of proteolytic cleavage, abrogates the ability of MEKK1 to signal JNK
Lin et al., Anticancer Res 2007 (Nasopharyngeal Neoplasms) : Moreover, for the first time in NPC cells it was demonstrated that the pathway involved in rhein induced apoptosis is caspase dependent, presumably through the endoplasmic reticulum ( ER ) stress pathway, as shown by an increase in the levels of glucose regulated protein 78 (GRP 78), PKR-like ER kinase (PERK), activating transcription factor 6 ( A TF6 ) and CCAA TIenhancer binding protein homologous protein ( CHOP ) as well as the activation of caspase-3 , -8, -9 and -12