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CASP8 — CEP41
Text-mined interactions from Literome
Troy et al., J Neurochem 2001
(Alzheimer Disease) :
Finally,
CEP-1347 blocked A beta stimulated activation of
caspase-2 and -3, placing these downstream of JNK activation
Wu et al., J Cell Biochem 2001
:
CEP treatment
induced activation of
caspase-9 and -3 accompanied by cleavage of PARP, Bid, lamin B1, and DFF45/ICAD in both Jurkat and K562 cells, whereas caspase-8 activation and Akt cleavage were observed only in Jurkat cells
Wu et al., Cell Signal 2002
(Leukemia...) :
Unexpectedly, pretreatment with a specific p38 inhibitor, SB203580, promoted
CEP induced apoptosis and
caspase activation in Jurkat and K562 cells, whereas pretreatment with an MEK-1 inhibitor PD98059 inhibited CEP induced apoptosis and caspase activation in K562 cells